Protein Details: Aquaporin-like protein 2

Protein ID

ICDB_Pro_0327

Protein Name

Aquaporin-like protein 2

Gene Name

AQY2; AQY2-2; YLL052C; L0590

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast)

Length

149 amino acids

AlphaFoldDB

AF-P0CD90-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across membranes. Involved in freeze tolerance; osmotolerance and cell flocculation in liquid cultures (By similarity). Is non-functional in most laboratory strains.

Sequence

MSNESNDLEKNISHLDPTGVDNAYIPPEQPETKHSRFNIDRDTLRNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALTTEPEGSHPGQLIMIALGFGFSVMFSIWCFWWGFEPSRFSLFVFGQSHLTSQMCSDVVSSDHCWDGCWWCR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1038/387s087; 10.1534/g3.113.008995; 10.1002/1097-0061(200007)16:10<897::aid-yea583>3.0.co;2-t; 10.1073/pnas.98.3.1000; 10.1038/nature02026

RefSeq

NP_013048.1